ObjectiveThe aim of this study is to explore the effects of early postnatal hyperoxia exposure combined with early ovalbumin (OVA) sensitization on lung inflammation and bacterial flora in neonatal mice on a juvenile mouse model of asthma.MethodsThirty-two newborn female C57BL/6 J mice were randomly divided into four groups, which including room ai

Renal cell carcinoma (RCC) is the most common type of kidney cancer.Increasingly evidences indicate that extracellular vesicles (EVs) orchestrate multiple processes in tumorigenesis, metastasis, immune evasion, and drug response of RCC.EVs are lipid membrane-bound vesicles in nanometer size and secreted by almost all cell types into the extracellul

Conodonts from the type region of the Oandu Regional Stage mohair torquay (Katian, Upper Ordovician) in NE Estonia were studied.Here, the lower boundary of the stage corresponds to a discontinuity surface at the base of the Hirmuse Formation and, in conodont succession, is marked by the disappearance of Semiacontiodus sp.and Besselodus? sp.The most

Declaration of smallpox eradication by the WHO in 1980 led to discontinuation of the worldwide vaccination campaign.The increasing percentage of unvaccinated individuals, the existence of its causative infectious agent variola virus (VARV), and the recent synthetic achievements increase the threat of intentional or accidental release and reemergenc

Biological structures possess excellent carolina force softball damage tolerance, which makes them attractive for ballistic protection applications.This paper develops a finite element modelling framework to investigate the performance of several biological structures that are most relevant for ballistic protection, including nacre, conch, fish sca